I Just Quit Nicotine
Gm gents. I just took a big break from nicotine. Completely reset my tolerance (1.5mg feels like 6mg now). It was effortless.
No withdrawals
No cravings
No side effects
But this protocol isn’t unique to nicotine, it applies to MOST chemical addictions, THC & Alcohol included. You see,
I’m going to show you exactly how I quit
If…
Nicotine doesn’t hit like it used to
You can’t go 3 hours without a zyn
You can rip 6mgs without breaking a sweat
Then this post is for you
This guide will cover:
How to use Nicotine for max nootropic potential
How to not get addicted in the first place
Supplement protocol for breaking your addiction (and stopping side effects)
Compounds to replace nicotine with
(For those wondering why I use nicotine in the first place, read this thread.)
Disclaimer: I am not a doctor. This is not medical advice. This is what I’ve used and recommended based on personal experience and scientific literature. Do your own research
Nicotine Has Legit Benefits
There’s a reason why nicotine is the most popular drug behind caffeine. It Works
Rapid Anti-depressant
Fast-acting stimulant
Disrupts default mode network (essential for ADHD focus)
Neuroprotective
I’ve been using nicotine off & on since I was 18. It quiets my brain & lets me focus on the task at hand. I’ve done more research on it than any other drug. I’m using it as we speak.
But regardless of its benefits, It must be cycled (this is law). Your brain & body are masters at adapting. Do something long enough and it becomes the new norm.
This is especially true for psychoactive substances (like nicotine)
Then why cycle?
Here’s a few legitimate reasons to cycle off of nicotine
Too much Glutamate
Too much vasoconstriction
Elevated blood pressure
Too high of tolerance
Too much of anything is no good. I notice more mental “static” when overdoing nicotine. I want to use the tool, not depend on it.
How to Use Nicotine The Right Way:
Nicotine is a NOOTROPIC. It should only be reserved for cognitively demanding tasks. Keep use to a minimum & stay in the goldilocks zone of stimulation (less is more)
You should never get “nic sick”. This is an overdose. You get all the negatives and none of the benefits.
I use NicNacs as they’re soft on the gums (xylitol coating) and slow dissolve. 1/4 of a 6mg or 1/3 of a 3mg.
I only use nicotine when writing, speaking, reading, or working. Casual nicotine use opens the door to addictive behavior.
My brain now associates the nicotine buzz with productivity. Law of association in action. And I want to KEEP it that way.
Nicotine Destim Protocol:
These are compounds I’ve found HIGHLY effective for a handful of addictions. Both behavioral and chemical. With plenty of research to back it up.
People coming off of Adderal, SSRIs & even benzos have found benefit with these compounds (not medical advice). But this works especially well with nicotine
BPC-157:
(500mcg/day)
Strong stabilizing effect on dopaminergic and serotonergic pathways. Essentially resets your brain back to homeostasis. Zero cravings for caffeine or nicotine while on it (and zero effect)
(Protocol for Oral BPC 157 Code: NOAH)
NAC:
(600mg 2x/day)
Modulates glutamate levels in the brain. Glutamate is primary excitatory neurotransmitter. Normalizes dopamine function (dysregulated by addiction). Shown to reduce cravings and addictive behaviors (great for OCD). Notably effective in cocaine and cannabis addictions (take notes, degenerates)
Niacin:
(100mg/2x day)
Great detox agent and seems particularly effective for smoking cessation. There’s actually a company trying to patent it for this use case. Dopamine plummets when withdrawing from nicotine. Niacin boosts dopamine production. Some say to combine with natural silica complex.
Agmatine Sulfate
(500mg 2-3x/day)
Modulates opioid receptors & NMDA receptors (glutamate). Agmatine’s been used forever to reset tolerance for drugs like Kratom and Adderall. Equally effective for other stimulants like nicotine & caffeine
Bonus: Thiamine
(100 mg 2x/day)
Nicotine, caffeine, and carbohydrates deplete Vitamin B1. Aside from addressing deficiencies, B1 gives a nice energy & dopaminergic boost, especially when coupled with carbohydrates
Caveat:
Resetting these “pleasure” & stimulus pathways can lead to blunted affect and desire. If you’re feeling particularly anhedonic (unable to feel pleasure/enjoyment), it might be the NAC or BPC 157. Keep tabs on how you feel and supplement with caution. Do your own research as always.
Nicotine Alternatives
Addiction carries a chemical and behavioral component. You need to separate the two.
You’re not just addicted to nicotine, you’re addicted to the repetitive motion of ripping a cigarette. Lighting it up, putting it in your mouth, inhaling deeply. Replace this with other similar stimuli
Vape → Aromatic diffuser, toothpicks
Zyns → Mints, Chewing gum
As for compounds. Here are a few that can mimic the Nicotinic acetylcholine receptor (nAChR) activation from nicotine:
Will these give you the same effects as nicotine? Probably not. But they have similar receptor activity and can replace that “buzz” stimulating feeling:
Theanine + Caffeine
L-tyrosine (with phenylalanine)
Acetyl L-Carnitine (ALCAR)
Rhodiola Rosea
Theacrine
If you’re struggling to quit, try this out. Use nicotine, don’t let it use you.
Godspeed.
Thanks for this Noah. Could you explain a little more about why resetting these pathways would lead to blunted affect? And what would you do if experiencing anhedonia, just discontinue?
Another good option for the pouch and dip boys are Tea Tree Mint toothpicks. They hit the tingly feeling and something to chew on/move around.